2022

• Cabello-Lobato M.J., Jenner M., Cisneros-Aguirre M., Brüninghoff K., Sandy Z., da Costa I.C., Jowitt T.A., Loch C.M., Jackson S.P., Wu Q., Mootz H.D., Stark J.M., Cliff M.J., Schmidt C.K. Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Nucleic Acids Res. 2022 Apr 14:gkac237.

2021

• Cabello-Lobato M.J., Jenner M., Loch C.M., Jackson S.P., Wu Q., Cliff M.J., Schmidt C.K. Microarray screening reveals a non-conventional SUMO-binding mode linked to DNA repair by non-homologous end-joining. bioRxiv. 2021 Jan 1;2021.01.20.427433.

2020

• Wu Q. Guardians of the genome: DNA damage and repair. Essays Biochem 2020; 64 (5): 683–685 (2020)

2019

• Wu Q. Structural mechanism of DNA-end synapsis in non-homologous end joining pathway for repairing double-strand breaks: bridge over troubled ends. Biochem. Soc. Trans. 47 (6), 1609-1619 (2019)

• Wu, Q., Liang, S., Ochi, T., Chirgadze, D.Y., Huiskonen, J.T., Blundell, T.L. Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways, Progress in Biophysics and Molecular Biology Oct 147:26-32 (2019)

2018

• Nishi, R., Wijnhoven, PW. G., Kimura, Y., Matsui, M., Konietzny, R., Wu, Q., Nakamura, K., Blundell T.L., Kessler B.M. The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage. Scientific Reports 8 (1), 17891 (2018)

• Dev, H., Chiang, T.-W. W. W., Lescale, C., de Krijger, I., Martin, A. G., Pilger, D., Coates, J., Sczaniecka-Clift, M., Wei, W., Ostermaier, M., Herzog, M., Lam, J., Shea, A., Demir, M., Wu, Q., Yang, F., Fu, B., Lai, Z., Balmus, G., Belotserkovskaya, R., Serra, V., O’Connor, M. J., Bruna, A., Beli, P., Pellegrini, L., Caldas, C., Deriano, L., Jacobs, J. J. L., Galanty, Y., Jackson, S. P. Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells. Nature cell biology 20 (8), 954-965 (2018)

• Wang, J. L.*, Duboc, C.*, Wu, Q.*, Ochi, T., Liang, S., Tsutakawa, S. E., Lees-Miller, S. P., Nadal, M., Tainer, J. A., Blundell, T. L., Strick, T. R. Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature structural & molecular biology 25 (6), 482-487 (2018)

2017

• Liang, S., Esswein, S. R., Ochi, T., Wu, Q., Ascher, D. B., Chirgadze, D., Sibanda, B. L., Blundell, T. L. Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached. Structural Chemistry 28 (1) 161-171 (2017)

2016

• Wu, Q.*, Paul, A.*, Su, D., Mehmood, S., Foo, T. K., Ochi, T., Bunting, E. L., Xia, B., Robinson C. V., Wang, B., Blundell, T. L. Structure of BRCA1-Abraxas complex reveals phosphorylation-dependent BRCT dimerization at DNA damage sites. Molecular Cell 61, 1-15 (2016)

2015

• Murray, J. E., van der Burg, M., IJspeert, H., Carroll, P., Wu, Q., Ochi, T., Leitch, A., Miller, E. S., Kysela, B., Jawad, A., Bottani, A., Brancati, F., Cappa, M., Cormier-Daire, V., Deshpande, C., Faqeih, E. A., Graham, G., Ranza, E., Blundell, T. L., Jackson, A. P., Stewart, G. S., Bicknell, L. S. Mutations in the NHEJ component XRCC4 cause primordial dwarfism. American Journal of Human Genetics 96, issue 3 412-424 (2015)

• Ochi, T., Blackford, A. N., Coates, J., Jhujh, S., Mehmood, S., Tamura, N., Travers, J., Wu, Q., Draviam, V. M., Robinson, C. V., Blundell T. L. and Jackson S. P. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science 347, 185-188 (2015)

• Wu, Q., Jubb, H., Blundell, T. L. Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif. Progress in Biophysics and Molecular Biology 117 (2-3), 143-148 (2015)

2014

• Ochi, T., Wu, Q. and Blundell, T. L. The spatial organization of non-homologous end joining: From Bridging to end joining. DNA Repair 17, 98-109 (2014)

2012

• Ochi, T., Wu, Q., Chirgadze, D. Y., Grossmann, J. G., Bolanos-Garcia, V. M. and Blundell, T. L. Structural insights into the role of domain flexibility in human DNA ligase IV. Structure 20, 1212-1222 (2012)

• Bolanos-Garcia, V. M., Wu, Q., Ochi, T., Chirgadze, D. Y., Sibanda, B. L. and Blundell, T. L. Spatial and temporal organization of multi-protein assemblies: achieving sensitive control in information-rich cell-regulatory systems. Phil. Trans. R. Soc. A.370, 3023-3039 (2012)

2011

• Wu, Q., Ochi, T., Matak-Vinkovic D., Robinson C.V., Chirgadze, D. Y. and Blundell, T. L. Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions. Biochem. Soc. Trans. 39, 1387-1392 (2011)

• Wu, Q., Sibanda, B. L., Ochi, T., Bolanos-Garcia, V. M., Blundell, T. L. and Chirgadze, D. Y. Spatial and temporal organisation of multiprotein systems of cell regulation and signalling: What can we learn from NHEJ system of Double-Strand break repair? Macromolecular Crystallography. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer Netherlands, Dordrecht, Ch. 1, 1-31 (2011)

2010

• Ochi, T, Sibanda, B. L., Wu, Q., Chirgadze, D. Y., Bolanos-Garcia, V. M. and Blundell, T. L. Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining. Journal of Nucleic Acids, 2010, 1-19 (2010)